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Open access Oct 2026

LineageFlow: growth-corrected state dynamics for probabilistic cell-fate prediction

Single-cell lineage tracing links early transcriptional states to the fates of their descendants, but forecasting clonal fate remains challenging because differentiation and unequal cell expansion jointly shape descendant populations. Here we introduce LineageFlow, a computational framework that combines continuous-tim...

Yang Liu, Qi Liu, Wei Wang et al. · 0 citations
Case report Open access Sep 2026

Case Report: Reversible central hypothyroidism-like thyroid dysfunction revealing ACTH-independent cushing syndrome during pregnancy

Thyroid dysfunction is common during pregnancy, and a reduced free thyroxine (FT4) concentration is often attributed to gestational thyroid disease. However, low FT4 with an inappropriately non-elevated thyroid-stimulating hormone (TSH), particularly when the abnormality persists during levothyroxine treatment, should...

Xin-Yu Li, Yu Wang, N. Gu et al. · 0 citations

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