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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Wei Sun

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Open access Aug 2026

Infliximab treatment affects the serum expression of matrix metalloproteinases MMP-2 and MMP-9 in Crohn's disease via the NLRP3 pathway, mediated by extracellular vesicle-derived RAGE

Infliximab modulates the balance of MMP- 2 and MMP-9 in CD patients, at least partly through inhibition of the EV-derived RAGE/NLRP3 inflammasome pathway, which may provide new therapeutic strategies and biomarkers for personalized treatment in Crohn’s disease.

Wei Li, Si-Si Chen, Wei Sun et al. · 0 citations

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