Nitroxyl (HNO), a short-lived reactive nitrogen species, participates in regulating cellular redox and nitrosative homeostasis, and its level fluctuations may reflect biochemical alterations associated with renal tubular injury during acute kidney injury (AKI). Therefore, the development of HNO fluorescent probes for A...
Zi-Yi Wang, Chao-Yue Wang, Ran Zhang et al.· Spectrochimica Acta Part A -...· 0 citations
Peroxynitrite (ONOO−) is a reactive oxygen species predominantly generated in mitochondria. Its concentration-dependent dynamics exhibit complex bidirectional effects, making quantitative measurement essential for understanding its pathological roles. Despite advances in fluorescent probes for ONOO− imaging, design l...
Ischemic stroke initiates with the interruption of cerebral blood flow, and reperfusion following revascularization may subsequently trigger cerebral ischemia-reperfusion injury. This secondary injury is characterized by dynamic molecular changes, including redox imbalance, mitochondrial dysfunction, blood-brain barrie...
