Acute pancreatitis (AP) is an acute inflammatory disorder of the exocrine pancreas with limited therapies. Whether cuproptosis, a copper-dependent cell death pathway, contributes to AP pathogenesis remains unknown. We integrated single-cell transcriptomics (GSE279876), single-cell transcriptomics (GSE188819), and human...
Qing-Feng Xie, Mao-Qin He, Qi Wang et al.· International Journal of Mol...· 0 citations
A compartment-specific “M-S-M-T” regulatory network in the DKD glomerulus and tubulointerstitium is proposed and will require validation in real-world microbiome, metabolomic and in vivo studies before any therapeutic inference can be drawn.
Feng-Wei Xie, Xiong-Wei He, Wen-Jie Chen et al.· Frontiers in Immunology· 0 citations
A context-dependent framework is proposed in which biallelic complete- or near-complete loss-of-function genotypes are interpreted as causative for FCS, whereas heterozygous variants are interpreted as predisposing to severe hypertriglyceridemia while retaining recognition of FCS carrier status.
Qi Yang, Wen-Bin Zou, Na Pu et al.· bioRxiv· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.