Author

Weilong Zhong

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Open access Oct 2026

PMEPA1 attenuates myocardial ischemia-reperfusion injury via interaction with NEDD4 and involvement of the TGF-β/SMAD pathway

Introduction Myocardial ischemia-reperfusion injury (MIRI) remains a significant challenge in cardiovascular medicine, and its molecular mechanisms are not yet fully elucidated. Methods In the present study, integrated transcriptomic analysis combined with machine learning identified PMEPA1 as a key gene consistently d...

Wei-Long Zhong, Ya-Nan Li, Bao-Ze Qu · Frontiers in Pharmacology · 0 citations

Open access Aug 2026

Stage-dependent upregulation of tumor-derived MDK is associated with CAF state remodeling and an ECM-rich immunosuppressive microenvironment in colorectal cancer

The data support a progression-linked association among tumor-cell-enriched MDK, CAF state remodeling, an ECM-high Fib-WNT5A program, and predicted collagen-mediated immune interactions in CRC.

Xia Liu, Siyuan Ma, Shuai Wu et al. · BMC Cancer · 0 citations