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Author

Weilie Xiao

2 papers indexed here

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Aug 2026

Euphiquorins A-E, five new structurally diverse diterpenoids from Euphorbia antiquorum L.

Phytochemical investigation of the whole plant of Euphorbia antiquorum led to the isolation of sixteen diterpenoids, including five new compounds, euphiquorins A-E (1, 5-8), together with eleven known analogues (2-4, 9-16), which were elucidated by comprehensive spectroscopic analyses and quantum chemical calculations.

Yuan-Lin Kong, Wei-Tao Yang, Ji-Lin Zhou et al. · 0 citations
Aug 2026

PGK1-driven histone lactylation fuels MDSC-driven immune evasion and tumor progression in triple-negative breast cancer.

Functional assays demonstrated that PGK1-driven glycolysis in TNBC cells promotes lactate accumulation and H3K18la, which subsequently induce transcriptional activation of CCL5 and recruitment of MDSCs, thereby impairing CD8+ T cell function and fostering an immunosuppressive tumor microenvironment that facilitates imm...

Yongpeng Wang, Wen-Zhen Dang, Zhendan Liu et al. · 0 citations

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