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Author

Wei Jin

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Open access Sep 2026

Chicken IDO2 and TDO2: Biochemical Characteristics and Regulatory Roles in Avian Tryptophan Metabolism and Inflammatory Response

Simple Summary Indoleamine 2,3-dioxygenase 2 (IDO2) and tryptophan 2,3-dioxygenase (TDO2) serve as rate-limiting enzymes for the kynurenine pathway. Distinct from mammals, chickens lack the IDO1 gene and rely exclusively on IDO2 and TDO2 for tryptophan catabolism. Supplemental dietary tryptophan increases the combined...

Wan-Li Li, Chen Zhang, Pin-Hui Wu et al. · 0 citations

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