N-acetylcysteine ameliorates oxidative stress-induced decline in sex hormone-binding globulin in HepG2 cells and polycystic ovary syndrome rats
Background Low sex hormone-binding globulin (SHBG) levels are a significant indicator of hyperandrogenism severity in patients with polycystic ovary syndrome (PCOS) and are associated with an increased risk of reproductive and metabolic diseases. Oxidative stress suppresses the production and secretion of SHBG. However...