HSPA12B modulates lung injury and neutrophil-related inflammatory responses in LPS-induced acute lung injury: a potential link to the PKC-PAD4 pathway.
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening conditions with high mortality. Excessive neutrophil activation and neutrophil extracellular trap (NET)-related responses, together with pulmonary endothelial barrier impairment, are critical pathological features. Heat shock pr...