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Open access Aug 2026

Rare metastatic clear cell renal cell carcinoma to pancreas and duodenum revealed by EUS-guided fine-needle biopsy

A 60-year-old male patient was diagnosed with clear cell renal cell carcinoma (ccRCC) 10 years ago (Figure 1) and underwent radical right nephrectomy. The patient recently presented with melena lasting 1 month. Gastroscopy revealed a mucosal elevation in the descending duodenum with an erythematous surface. An adjacent...

Xiao-Rong Tian, Wei Du, Yu-Yan Zhou et al. · 0 citations
Open access Sep 2026

Targeting PGAM5-Drp1 axis modulates mitochondrial dynamics and inhibits pancreatic acinar cell necroptosis in severe acute pancreatitis

Severe acute pancreatitis (SAP) is a high-mortality disease characterized by extensive pancreatic necrosis and uncontrolled inflammation. Mitochondrial dysfunction and pancreatic acinar cells (PACs) necroptosis are critical pathological events in SAP, while the role of the mitochondrial protein phosphoglycerate m...

Xiao-Rong Tian, Wei Du, Yu-Yan Zhou et al. · 0 citations

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