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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Wei-Dong Zang

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Open access Sep 2026

The primary somatosensory cortex mediates trigeminal neuralgia induced depressive-like behaviors through an indirect pathway targeting the lateral habenula

Trigeminal neuralgia frequently co-occurs with depression, aggravating clinical outcomes. The primary somatosensory cortex (S1), a key pain-processing region, exhibits hyperactivity linked to chronic pain. Moreover, S1 integrates nociceptive inputs to modulate pain-related affective disturbances. However, it rema...

Yuan-Zeng Wang, Tian-En Si, Ying-Ying Zhang et al. · 1 citation
Review Open access Sep 2026

Deep brain stimulation mechanisms in comorbid pain and emotional dysregulation from animal models

This mechanism-based framework outlines a translational roadmap for personalized neuromodulation, guiding symptom-specific target selection and the development of biomarker-driven, closed-loop DBS systems to concurrently treat pain and affective pathologies.

Tian-En Si, Hao Han, Ying-Ying Zhang et al. · 0 citations

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