MaR1 and NGF co-treatment promotes sciatic nerve repair by modulating GSK-3β/NF-κB signaling and suppressing inflammasome-mediated pyroptosis.
OBJECTIVE This study aimed to investigate the therapeutic effects of Maresin 1 (MaR1) combined with nerve growth factor (NGF) on peripheral nerve injury (PNI) repair and to explore whether the underlying mechanism is associated with the regulation of GSK-3β/NF-κB signaling and inflammasome-mediated pyroptosis. METHOD...