The inadequate nerve networks in regenerated bladders remain a significant challenge in bladder tissue engineering. Our previous studies have demonstrated that incorporating basic fibroblast growth factor (bFGF) and urine‐derived stem cells (USCs) into bladder acellular matrix (BAM) enhances bladder repair. While these...
Noninvasive differentiation of malignant and benign renal masses remains a major clinical challenge, particularly for radiologically indeterminate lesions. Here, we developed and validated a plasma cell-free DNA (cfDNA) fragmentomics-based machine learning classifier for renal mass characterization. The model was train...
Lin-Fei Li, Cong Wang, Song Wang et al.· Molecular Biomedicine· 0 citations
A structure-function landscape for aptamers is introduced, constructed by systematic single-point mutagenesis that maps the contribution of each nucleotide to target binding and highlights its potential to guide the development of high-performance biosensors.
Zhuoer Chen, Qi Sun, Xian-Lu Lei et al.· Analytical Chemistry· 0 citations
The rapid and specific detection of foodborne bacteria in complex matrices remains a critical analytical challenge. Conventional nucleic acid amplification and immunological methods offer high analytical sensitivity, but they often provide limited information on bacterial viability because nucleic acids and antigenic e...
Xingying Mou, Xin-Ge Cui, Yongkang Zhang et al.· In Analysis· 0 citations
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