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A photocurable composite bioadhesive hydrogel (GelMA-QAS/DMA@HAP) as a minimal invasive surface coating for the management of caries through synergistic antibacterial and remineralization pathways is developed.
A dynamic stiffness hydrogel system designed to mimic the stiffness variation of the ECM during bone repair, based on a 3D interpenetrating polymer network, that exhibited the ability to repair critical‐sized bone defects, underscoring its therapeutic potential.
Overall, this study provides a pH-responsive, nanozyme-integrated fibrous membrane with combined antibacterial and pro-regenerative functions, offering a promising strategy for the treatment of bacteria-infected wounds without relying on antibiotics.
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