Author

Wei-Bo Dai

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Aug 2026

A novel renoprotective mechanism of Phellodendri Chinensis Cortex in uric acid nephropathy: targeting PFKFB3-glycolysis-macrophage axis.

ETHNOPHARMACOLOGICAL RELEVANCE Phellodendri Chinensis Cortex (PCC), a classic herb for "clearing heat and drying dampness," is traditionally used to treat gout and uric acid nephropathy (UAN) for its urate-lowering and nephroprotective properties. Yet, the mechanism of its direct renoprotective effect remains unclear....

Xinyi Li, Qing Luo, Zi-Kang Li et al. · Journal of Ethnopharmacology · 0 citations

Open access Jul 2026

Cimicifuga foetida L. polysaccharide alleviates ulcerative colitis by inhibiting pyroptosis and regulating gut microbiota

The preliminary biological assessment suggests that the polysaccharide subfraction SM05 alleviated the symptoms of UC induced by DSS, and may be related to the activation of the Nrf2/Keap1 pathway, the inhibition of pyroptosis, and the regulation of the intestinal microbiota.

Qing Luo, Yangyang Xu, Zhihua Li et al. · Frontiers in Pharmacology · 0 citations