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Author

Wang Zhang

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Open access Sep 2026

PiuA promoter mutations confer cefiderocol resistance in Acinetobacter baumannii: from in vitro evolution to global genomic screening

Introduction Carbapenem-resistant Acinetobacter baumannii (CRAB) poses a global health threat due to limited therapeutic options. Cefiderocol, a novel siderophore-conjugated cephalosporin, demonstrates potent in vitro activity against a variety of Gram-negative bacteria, including CRAB. However, cefiderocol's recent in...

Xiao-Chen Liu, Qing-Ye Xu, Jin-Tao He et al. · 0 citations

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