Sep 2026
A Detergent-Free Sample Preparation Method Enabling Desalting-Free Tandem PTM Enrichment
Mass spectrometry (MS)-based proteomics is a powerful tool for analyzing post-translational modifications (PTMs). However, conventional multiplexed PTM enrichment workflows typically require denaturing detergents and subsequent time-consuming desalting steps, which inevitably lead to sample loss. Here, we present a d...
Zhan-Peng Lin, Xin-Yan Gao, Cheng-Wen Wen et al.
· Journal of Proteome Research · 0 citations