Author

Wanyu Wang

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Oct 2026

Berberine increases the sensitivity of sorafenib in human hepatocellular carcinoma via inducing HIF-1α-mediated energy crisis.

BACKGROUND Hepatocellular carcinoma (HCC) often develops resistance to sorafenib (SORA), a multikinase inhibitor that has long been a cornerstone of systemic therapy for advanced HCC, leading to cancer progression and poor survival. Strategies to enhance the therapeutic efficacy of SORA in HCC are therefore urgently ne...

Wei Guo, Zi-Xin Feng, Ming-Hsien Hu et al. · Phytomedicine · 0 citations

Review Open access Aug 2026

The chemokine network in triple-negative breast cancer: its role in immune microenvironment regulation, and prospects for targeted therapy

A roadmap is provided for navigating chemokine network complexity, distilling actionable insights for clinical translation, and defining priority research directions to overcome current bottlenecks in TNBC chemokine-targeted therapy.

Wanyu Wang, Linhua Chen, Wei Guo et al. · Frontiers in Immunology · 0 citations