Plasmonic metal nanoparticles for studying complex interactions and dynamics in biological systems using surface-enhanced raman spectroscopy: insights from biofilms
This PhD thesis addresses the challenges posed by complex biological systems on molecular detection and analysis using biofilms as a model system. Biofilms, with their sticky and heterogeneous extracellular matrix of polysaccharides, proteins and nucleic acids, exhibit strong matrix interference. The presence of multip...