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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

W. V. D. van de Berg

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3 papers indexed here

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Open access Sep 2026

Interrogating DNA methylation associated with Lewy body pathology in a cross brain-region and multi-cohort study

Here, we conduct a large meta-analysis of DNA methylation across multiple cortical brain regions, in relation to increasing burden of Lewy body pathology. Utilizing a dataset of 1205 samples (832 unique donors), we identify 24 false discovery rate significant differentially methylated loci associated with Lewy body...

Joshua Harvey, J. Imm, Morteza Kouhsar et al. · 0 citations
Open access Sep 2026

Cryo-ET and Sub-Volume Analysis of Fibrillar Pathology in the Neurodegenerative Human Brain

Structural studies of amyloid fibrils extracted from brain tissue have identified disease-specific fibril polymorphs. However, the mechanisms driving distinct polymorphs remain unclear because no method currently links the cellular context, composition and ultrastructure of individual aggregates to their constituent fi...

Lukas van den Heuvel, Daniel A. Stähli, Julika Radecke et al. · 0 citations
Open access Sep 2026

Lysosomal Expression Profile in Plasma Associates with Disease Severity in Parkinson's Disease.

These findings support the use of pathway-specific biomarkers for improving PD diagnostics and monitoring disease progression and support the use of pathway-specific biomarkers for improving PD diagnostics and monitoring disease progression.

Janna van Wetering, M. V. van Ingen, Evelien Timmermans et al. · 0 citations

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