Author

W. Phoolcharoen

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#protein folding Open access Sep 2026

Fusion Partner and ER-Retention Signal Are Associated with Distinct Host Proteomic and Metabolic Responses During Interleukin-15 Production in Nicotiana benthamiana

Plant molecular farming has emerged as a promising platform to produce recombinant biopharmaceuticals. The expression of foreign proteins changes the host proteome and metabolome, and these changes might have an effect on the accumulation of recombinant proteins. In this study, we investigated how fusion partners and E...

A. Savinova, Pipob Suwanchaikasem, Balamurugan Shanmugaraj et al. · Plants · 0 citations

Open access Jul 2026

Comparative proteomics and metabolomics reveals distinct host protein quality control and metabolic signatures during recombinant IL1-His and IL15-His expression in Nicotiana benthamiana

Findings underscore that the characteristics of the target protein and its interaction with the host's physiology could influence the yield of the recombinant protein production in plants.

A. Savinova, Theerakarn Srisangsung, Pipob Suwanchaikasem et al. · PLoS ONE · 0 citations