The contribution of the gut microbiome to chronic heart failure (HF) remains poorly defined. We performed integrated microbiome and host multi-omic profiling of adults with chronic systolic HF due to nonischemic cardiomyopathy (n = 59) and healthy participants (n = 50), including longitudinal sampling in some cases. He...
Petra Mamic, Han-Duo Shi, Wen-Yu Zhou et al.· Nature Cardiovascular Resear...· 0 citations
Acute heart failure remains a high-morbidity, high-mortality syndrome with heterogeneous clinical presentations, ranging from congestion, a frequent driver of hospitalization and central therapeutic target, to hypoperfusion and cardiogenic shock in more severe phenotypes. Yet, bedside findings have limited diagnostic a...
Francisco B. Alexandrino, S. Augusto, W. H. Wilson Tang· Journal of the American Hear...· 0 citations
Background: Clinical genetic evaluation for patients with dilated cardiomyopathy (DCM) is minimally implemented and models of care are not defined. To understand current genetics care for DCM, a systematic needs assessment was conducted. Methods: Principal Investigators (PIs) of the DCM Consortium convened at the Summe...
E. Jordan, T. Moscarello, Hibatallah Khafagy et al.· Circulation: Heart Failure· 0 citations
In patients with cirrhosis-associated HOHF, disproportionate left atrial remodeling, elevated CI, and higher Ees were associated with mortality, which supports further evaluation of integrated invasive hemodynamic and quantitative echocardiographic assessment for characterizing risk-related phenotypes in cirrhosis-asso...
Satoshi Miyashita, Raquel Lamarche, P. Oro et al.· Frontiers in Cardiovascular...· 0 citations
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