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W. Dowjat

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Open access Jul 2026

Overexpression of DYRK1A in down syndrome: Analysis of kinase activity

It is shown that DYRK1A activity elevation in DS is in parallel to that of DYRK1A protein level regardless of the status of kinase phosphorylation, which suggests that DYRK1A catalytic activity in DS is mainly regulated by protein level.

W. Dowjat, Y. Hwang · Biochemistry and Biophysics... · 0 citations