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W. Dermauw

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Open access Sep 2026

Interfering with DNA repair pathways to enhance CRISPR-Cas9-mediated homology-directed repair in a chelicerate genetic model

This work provides the first functional analysis of double-strand break repair in a chelicerate of T. urticae, and demonstrates that Polθ-deficient strains enhance incorporation of repair templates, even when mutations are distant from the cut site.

S. De Rouck, W. Dermauw, T. van Leeuwen · 0 citations

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