Metronomic decitabine offers a patient-centered frontline therapeutic approach for TP53 -mutated complex-karyotype myeloid neoplasms
Jonathan A. Webster, Lukasz P. Gondek, Mark J. Levis et al.
· 0 citations
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Open access
Oct 2026
Metronomic decitabine with venetoclax offers a patient-centered frontline therapeutic approach for TP53-mutated complex-karyotype myeloid neoplasms.
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L. Walsh, Royce P. Lee, Joanathan Pan et al.
· Haematologica · 0 citations
Open access
Aug 2026
Targeting EZH2 Oncogenic Splicing: Decoding the Regulatory Network and Antisense Correction
This study instigated a gene-specific targeted strategy by unlocking the regulatory network, and designed antisense oligonucleotides (ASOs) targeting important regulatory sites, demonstrating that ASO pharmacology is an actionable strategy for clinical development, challenging the existing paradigms in SF-mutated cance...
Md Rafikul Islam, Preeti Nagar, Naomi McNaughton et al.
· Genes & Development · 0 citations