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W. Brugmann

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Sep 2026

Abstract A002: Epigenetic Regulation of the GDF15 Immune Checkpoint Determines Sensitivity of Atypical Teratoid/Rhabdoid Tumors to Natural Killer Cell Immunotherapy

Atypical teratoid/rhabdoid tumors (ATRTs) are highly aggressive pediatric central nervous system malignancies characterized by poor clinical outcomes despite intensive multimodal therapy, including surgery, chemotherapy, and radiation. Although molecular classification has improved our understanding of ATRT biology,...

V. Gopalakrishnan, Jyothishmathi Swaminathan, Ben Ho et al. · 0 citations

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