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W. Ahsan

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Open access Sep 2026

Design, synthesis, and preliminary anticancer evaluation of diphenylpropan-1-one derivatives: in vitro, in vivo and in silico studies

A series of diphenylpropan-1-one (DPP) derivatives (4a–4i), rationally designed around a chalcone framework and synthesized via a three-step reaction sequence demonstrated encouraging preliminary anticancer potential and may serve as promising lead molecules for future investigations.

A. Najmi, M. S. Alam, W. Ahsan et al. · 0 citations
Review Open access Jun 2026

Machine Learning-Guided Enzyme Engineering Approaches for Enhanced Biocatalytic Efficiency: Concepts, Mechanisms, and Future Directions

This review provides a comprehensive overview of ML-guided strategies to improve key enzymatic parameters, including the turnover number, substrate affinity, and catalytic efficiency, with a focus on mechanistic insights and performance outcomes.

W. Ahsan · 0 citations

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