Multi-target drugs possess significant therapeutic potential for the therapy of complex diseases and drug-resistant conditions. Based on this fact, isatin-pyrazole derivatives, namely, 5-substituted isatin-pyrazole derivatives 7a-d and N-alkyl isatin-pyrazole derivatives 9a-d, were prepared by merging the pyrazole moti...
Mohamed A. Al-Omar, H. Alkahtani, M. A. Bhat et al.· Bulletin of the Chemical Soc...· 0 citations
A novel series of six imidazopyridine-based chalcone hybrids is synthesized and evaluated their in vitro biological activities, including total antioxidant capacity, iron-reducing power, and radical scavenging (DPPH, ABTS, NO), as well as antidiabetic potential against α-amylase, α-glucosidase, and aldose reductase.
Hanan Abdelmawgoud Atia, Aladdin M. Srour, Hanaa Farag et al.· Scientific Reports· 0 citations
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