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Vitalii O. Usenko

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Review Open access Oct 2026

PATHOPHYSIOLOGICAL MECHANISMS LINKING CHRONIC STRESS TO ALTERED DRUG RESPONSE: A NARRATIVE REVIEW OF PHARMACOKINETIC AND PHARMACODYNAMIC CONSEQUENCES

Introduction. Interindividual variability in drug response is conventionally attributed to genetic polymorphism, age, sex, organ function, comorbidity, adherence, diet and drug–drug interactions. This framework tacitly assumes that the physiological environment of pharmacotherapy is stable. Sustained psychological stre...

Galyna A. Cordero, M. Khaitovych, V. V. Udovytskyi et al. · 0 citations

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