Hippocampal metabolites illustrate greater potential for early response assessment to antidepressant therapy than the anterior cingulate cortex in major depressive disorder.
Major Depressive Disorder (MDD) is a psychiatric disorder associated with altered neuro-metabolism. This study investigated the effect of antidepressant therapy on the metabolism of the right hippocampus and anterior cingulate cortex (ACC) in patients with MDD, using in vivo proton magnetic resonance spectroscopy (MRS)...