Vijay Kumar Simhadri

Halogen bond-assisted radical relay cyclization to access alkynylated 2-pyrrolidones.

In the present work, we disclose a photoinduced synthesis of diverse alkynylated 2-pyrrolidones from N-allylanilides and arylacetylene bromides in moderate to good yields. The protocol operates under mild, catalyst-free conditions and employs inexpensive starting materials. Preliminary mechanistic studies support the i...