Open access
Sep 2026
Age-Dependent Remodeling of Parvalbumin Interneuron-Associated Networks Alters Corticospinal Output in the Motor Cortex
The primary motor cortex (M1) controls voluntary movements through coordinated interactions between excitatory pyramidal neurons and inhibitory parvalbumin-expressing interneurons (PV-INs). Although PV-INs are critical to regulating motor output and motor coordination, their role in age-related motor decline remains un...
Xiao-Fei Wei, Istvan Mody, Yi-Xin Wu et al.
· Current Issues in Molecular... · 0 citations