Association Between Pre-Existing Anti-Diphtheria Toxoid IgG and Immune Responses to a CRM197-Conjugated 14-Valent Pneumococcal Conjugate Vaccine in Infants: A Post Hoc Analysis of a Multicenter Phase III Trial
Pre-existing anti-diphtheria toxoid IgG measured before vaccination was not associated with a consistent reduction in post-primary serotype-specific pneumococcal IgG responses to CRM197-conjugated BE-PCV14, and analyses stratified by baseline pneumococcal IgG similarly showed no consistent evidence of reduced responses...
S. Thuluva, S. Gunneri, S. Ningaiah et al.
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