Open access
Aug 2026
Regulation of the histone H3K36 methyltransferase Set2 by the histone chaperone Spt6
Abstract Histone H3 lysine 36 methylation is a conserved histone modification that is critical for maintaining eukaryotic transcriptional fidelity and genomic stability. In Saccharomyces cerevisiae, this modification is catalyzed by Set2, an ortholog of the mammalian H3K36 methyltransferase SETD2. Previous genetic, bio...
Alexandra R. Elchert, Vanda Lux, James L. Warner et al.
· Nucleic Acids Research · 0 citations