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Vamshi Krishna Tippavajhala

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Open access Sep 2026

Molecular Mechanisms and Therapeutic Applications of Extracellular Vesicles in Remodeling of the Skin Cancer Niche

Skin cancer, encompassing melanoma and nonmelanoma types, is an escalating global health issue owing to its increasing prevalence, invasiveness, and spreading capability. Extracellular vesicles (EVs) have become pivotal agents of intercellular communication in the tumor microenvironment (TME). These nano‐ to microscale...

Megha Kotian, Maria Nison, Deepanjan Datta et al. · 0 citations
Open access Aug 2026

Analytical quality by design based HPLC method development validation and green assessment for tenofovir alafenamide quantification in ultradeformable vesicles

QbD makes it easy to develop an analytical method using a logical process to evaluate and control critical characteristics for robustness and ruggedness, providing more reliable methods than traditional trial-and-error approaches. It enables understanding of critical factors affecting product performance. The HPLC me...

Raagul Seenivasan, Praveen Halagali, P. Nayak et al. · 0 citations
Review Open access Aug 2026

Advances in gene transfer technologies: comparing viral and non-viral vectors for therapeutic applications

This review provides a comprehensive overview of the current status of viral and non-viral vector systems for in vivo and ex vivo applications, and key comparisons are made across safety, efficacy, scalability, and immune responses.

Praveen Halagali, Raagul Seenivasan, Amatha Sreedevi et al. · 1 citation

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