Author

Valentina Pecchioli

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Open access Jul 2026

Thioredoxin Reductase as a Target for Antibacterial Gold Compounds in Burkholderia cenocepacia: Disclosing the Molecular Basis of Enzyme Inhibition

Thioredoxin reductase from Burkholderia cenocepacia (Bc‐TrxR) is a recognized intracellular target of antibacterial gold(I) compounds, yet the molecular basis of enzyme inhibition remains unclear. Here, we report an integrated structural, biophysical, and biochemical investigation of recombinant Bc‐TrxR and its interac...

Stefano Zineddu, José Aleixo de Azevedo-França, Martina Aguanno et al. · ChemBioChem · 0 citations

Open access Jul 2026

Exploring the Role of Azurin from the Endophytic Bacterium Pseudomonas sp. OHS18 Through the Phenotypic Characterization of a Δazu Mutant

New insights are provided into the physiological role of azurin in environmental bacteria and its involvement in bacterium–eukaryote interactions is suggested, thereby opening new perspectives for biotechnological and biomedical applications.

Giulia Semenzato, Veronica Ghini, Valentina Pecchioli et al. · Microorganisms · 0 citations