Computational Design and Experimental Validation of Photoactive PARP1 Inhibitors
Abstract Light-activated drugs are a promising way to treat localized diseases for which existing treatments have severe side effects. However, their development is complicated by the set of photophysical and biological properties that must be simultaneously optimized. Here we used computational techniques to find a se...
Simon Axelrod, Miroslav Kašpar, Kristýna Jelínková et al.
· Journal of the American Chem... · 0 citations