Author

V. V. Pupykina

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Open access Sep 2026

Dynamics of intima‑media complex thickness in children with familial hypercholesterolemia on the background of lipid‑lowering therapy: A retrospective study of real clinical practice data

Introduction. Pediatric familial hypercholesterolemia (FH) is characterized by prolonged exposure to elevated low-density lipoprotein cholesterol (LDL-C) and early development of subclinical vascular injury. Carotid intima-media thickness (cIMT) is a widely used ultrasound marker of vascular phenotype in children; t...

I. I. Pshenichnikova, I. N. Zakharova, I. M. Osmanov et al. · Meditsinskiy sovet = Medical... · 0 citations

Review Open access Oct 2026

Disorders of gut-brain interaction: discussing the new Rome V criteria. A review

For a long time, gastrointestinal disorders in children remained a "gray area" in clinical medicine, as the term "functional disorder" created the impression that the problem was of secondary importance. However, in recent years, it has become evident that this term conceals a complex, multi-component pathology affecti...

I. N. Zakharova, V. V. Pupykina, Y. Orobinskaya et al. · Pediatrics. Consilium Medicu... · 0 citations

Review Open access Sep 2026

Experts resolution on the topic “Probiotics in pediatric surgery: Challenges and opportunities”

Experts resolution assess the role of probiotics in pediatric surgery and address a practical question: should probiotics be prescribed concomitantly with antibiotics? The paper examines how surgical stress, limited enteral feeding, and antibiotic therapy in children disrupt the gut microbiota and increase the risk o...

I. N. Zakharova, A. Gorelov, I. M. Osmanov et al. · Meditsinskiy sovet = Medical... · 0 citations