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Author

V. Upasani

2 papers indexed here

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Open access Oct 2026

A TLR2-associated entry pathway promotes productive dengue virus serotype 2 infection and inflammatory responses in classical monocytes

Severe dengue is characterized by systemic inflammation and vascular leakage. Recent evidence indicates that Toll-like receptor 2 (TLR2) supports early steps of dengue virus (DENV) infection in monocytes, whereas intracellular viral RNA sensing drives much of the subsequent inflammatory response. However, whether this...

J. Castillo, M. Punekar, V. Upasani et al. · 0 citations
Review Open access Sep 2026

Functional antibody responses and protection against symptomatic dengue

Exposure to dengue virus (DENV) triggers the development of anti-viral antibodies that may contribute to either protection or disease progression. Antibodies exist in different isotypes and subtypes, with diverse specificities and functions. IgG antibodies are produced during primary and secondary DENV infections, wher...

C. L. Chua, H. T. M. Vo, C. B. L. Victorio et al. · 1 citation

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