Open access
Aug 2026
Peptide exchange–competent class I MHC molecules produced in eukaryotic cells for rapid production of MHC multimers
A novel method is presented for the expression in eukaryotic cells of secreted peptide exchange–competent class I MHC proteins in their native conformation and it is demonstrated that tetramers produced in this way are equivalent to conventionally produced tetramers for T-cell staining.
V. Ramachandiran, J. Shires, Richard A. Willis et al.
· Journal of Immunology · 0 citations