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V. Orlando

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Review Open access Oct 2026

The therapeutic potential of transposable element activity modulation.

The reactivation of transposable elements (TEs) is a recurrent molecular event across cancer, neurodegeneration, autoimmune disease, and aging, yet its therapeutic implications remain largely unexplored. Normally repressed under strict epigenetic surveillance, reactivated transposable elements can generate immunostimul...

Gabriele Morelli, M. D'Onghia, Arianna Mangiavacchi et al. · 0 citations

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