Author

V. Miroshnikova

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Open access Aug 2026

Reverse Cascade Genetic Screening for Revealing New Cases of Familial Hypercholesterolemia in Russia: Pilot Project.

BACKGROUND Reverse cascade genetic screening, following initial lipid testing, is an effective strategy for the early diagnosis of familial hypercholesterolemia (FH) and related hereditary dyslipidemias. In this study, we present the results of a pilot project in Russia. METHODS This was a hybrid retrospective-prospe...

V. Miroshnikova, A. Izyumchenko, N. N. Smirnova et al. · Frontiers in Bioscience · 0 citations

Open access Jul 2026

Decreased expression of the PPARG, ADIPOQ, and SLC2A4 genes in subcutaneous adipose tissue in bariatric patients with morbid obesity and type 2 diabetes mellitus

The development of T2DM on the basis of obesity and BMI of more than 35 kg/m 2 is associated with reduced expression levels of the PPARG, ADIPOQ, LEP, LEP and SLC2A4 genes in SAT and VAT, and changes in gene expression in obesity were associated with a decrease in adiponectin and an increase in leptin serum concentra...

V. Miroshnikova, K. Dracheva, M. Grunina et al. · Obesity and Metabolism · 0 citations