Author

V. Masand

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Open access Aug 2026

A Topological and Spatial Analysis of FDA‐Approved Drugs, Blood‐Brain Barrier Permeants, Natural Products, and Metabolites

In this study, we present a comprehensive structural analysis of four distinct chemical libraries: FDA‐approved drugs, blood‐brain barrier (BBB) permeable agents, natural products (UNPDA), and human metabolites. Our multidimensional profiling reveals fundamental divergences in molecular architecture. While synthetic dr...

V. Masand, S. Al-Hussain, Mohammed Sharique Ahmed Quadri et al. · ChemMedChem · 0 citations

Review Open access Oct 2026

Organelle-Targeted Nanocarriers for Cancer Therapy: Design Principles, Intracellular Trafficking, and Translational Barriers in Precision Drug Delivery

Abstract The clinical translation of cancer nanomedicine remains constrained by inefficient intracellular delivery, poor subcellular specificity, and limited tumor accumulation, highlighting the need for more precise drug delivery strategies. Organelle-targeted nanocarriers have emerged as a promising platform for enha...

Han-Gen Zhang, Jia Guo, Xin-Miao Wang et al. · International Journal of Nan... · 0 citations