Store-operated calcium signaling modulators improve a dendritic cell-based vaccine against melanoma
ABSTRACT Dendritic cells (DCs) are crucial for eliciting cytotoxic CD8+ T cell responses against intracellular pathogens, viruses, and cancer. DC-based vaccines can stimulate both cytotoxic and humoral immunity, as well as memory against cancer. However, efficacy has remained low, leaving room for improvement. Our prev...