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V. Karev

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Open access Aug 2026

Experimental evaluation of high-dose L-ornithine L-aspartate in nonalcoholic steatohepatitis and its extrahepatic complications

Introduction. In preclinical studies using models of nonalcoholic steatohepatitis (NASH), L-ornithine L-aspartate (LOLA) at 1.5 g/kg/day, a dose equivalent to the recommended human dose of 9 g/day, attenuated not only liver injury but also neuropsychiatric and skeletal muscle complications. The possibility of using...

V. A. Prikhodko, T. M. Matuzok, K. S. Doroshchuk et al. · 0 citations

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