Open access
Aug 2026
Tail—aware heterogeneous graph neural networks for multi—class drug—drug interaction prediction
Among class imbalance strategies tested, Tail-Aware Focal Loss outperforms standard cross-entropy by 3.1% on Macro F1 and 7.4% on Recall, striking a better balance between class performance than either weighted cross-entropy or weighted random sampling.
Varshini Venkatesh, Varsha G, Dhannya S. M.
· Bioinformatics · 0 citations