Author

V. Dobričić

3 papers indexed here

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Open access 2026

Molecular docking as a tool in drug discovery and protein-ligand interaction analysis

Molecular docking emerged as an irreplaceable technique of structure-based drug design, revolutionizing the early stages of modern drug discovery since its introduction in the 1980s. Docking is widely used in the rational drug development to estimate binding affinity of newly designed compounds to active sites of selec...

J. Savić, M. Miličević, V. Dobričić et al. · Zbornik radova · 0 citations

Open access Oct 2026

Oxaprozin-Based Amide Derivatives as Multifunctional Agents: Synthesis, Characterization, and Comprehensive Biological Profiling

Background/Objectives: Inflammation plays a role at multiple levels, contributing to tumorigenesis, cellular proliferation, cell survival, and metastasis. The established link between chronic inflammation and tumor development has shifted the therapeutic focus toward nonsteroidal anti-inflammatory drugs, which exert th...

Anđela Gogić, Miloš Nikolić, Nikola V. Nedeljković et al. · Pharmaceutics · 0 citations

Aug 2026

Design of fluorinated triazinoindoles as highly potent and markedly selective ALR2 inhibitors: synthesis, in silico and in vitro evaluation of promising lead compounds.

This study demonstrates that strategic fluorination is an effective approach for improving the potency and selectivity of ALR2 inhibition and identifies (8-F)OTI as a promising lead compound for further optimization and biological evaluation.

L. Kováčiková, Terezia Teplanova, M. Májeková et al. · Bioorganic chemistry (Print) · 0 citations