Abstract Summary Small RNA sequencing enables high-throughput profiling of diverse small non-coding RNAs, but their complex biology creates substantial bioinformatic challenges. Conventional gene-centric pipelines often discard multi-mapping reads or impose arbitrary feature assignments, leading to biased quantificatio...
K. Trachtová, D. Al Tukmachi, V. Bystrý et al.· Bioinformatics Advances· 0 citations
The SeqUIaSCOPE platform combines molecular-level validation via embedded genome browsing with systems-level interpretation through dynamic pathway visualization, enabling geneticists to assess how alterations converge across biological networks.
Kateřina Jurásková, P. Pokorna, Kristián Kováč et al.· Bioinformatics· 0 citations
PUDU (Pipeline for Universal Diversity Unveiling), a modular Snakemake workflow that supports amplicon (short-read 16S), shotgun metagenomics (WGS), and long-read 16S analyses from raw reads to standardized outputs for downstream microbial ecology, is presented.
Alejandro Medaglia-Mata, Pablo Rojas-Rodríguez, V. Bystrý et al.· Frontiers in Bioinformatics· 0 citations
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