Uyen Pham

Identifying common G protein–coupled receptor interacting proteins independent of heterotrimeric G proteins and β-arrestins

Abstract The canonical paradigm of G protein–coupled receptor (GPCR) signaling recognizes G proteins, β-arrestins, and GPCR kinases as the primary transducers that shape GPCR signaling. However, multiple studies have demonstrated that other interacting proteins regulate GPCR function in addition to these pathways, term...