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Author

Usama Ishaq Abdulrazak

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Review Open access Sep 2026

Safety and Efficacy of Rational Polytherapy with Sodium Valproate and Lamotrigine for Pediatric Drug-Resistant Epilepsy: A Systematic Review and Meta-Analysis

Background: Drug-resistant epilepsy (DRE) affects approximately one-third of individuals with epilepsy, where seizures remain uncontrolled despite appropriate trials of at least two antiseizure medications (ASMs). Neuroinflammation, specifically chronic microglial activation, plays an important role in epileptogenesis,...

A. M. Abdullahi, Usama Ishaq Abdulrazak, A. Z. Abdurrahman · 0 citations

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